Correlation of cell‐surface CD 8 levels with function, phenotype and transcriptome of naive CD 8 T cells

Unique Features of Naive CD 8

Rapid Effector Function in CD 8 1 Memory T Cells

The nature of the CD8 1 T cells that underlie antiviral protective immunological memory in vivo is unclear. We have characterized peptide-specific CD8 1 T lymphocytes directly ex vivo from peripheral blood in humans with past exposure to influenza virus, using single cell interferon g (IFNg ) release as a measure of effector function. In individuals in the memory state with respect to influenza...

IFN - T Cell Subsets to Express IL - 18 Receptor − CD 8 − , and CD 4 + , CD 8 + Differential Capacities of CD

CD 2 Regulates the Positive Selection and Function of Antigen - Specific CD 4 Ï CD 8 " T Cells

The CD2 glycoprotein has been implicated in both positive ment of positive selection, the lack of CD2 was associated and negative regulation of T-cell mitogenesis. To study the with defects in proliferative responses and interferon-g proinvolvement of CD2 in T-lymphocyte development and imduction when transgenic thymocytes and mature T lymphomune responses, we have analyzed two lines of CD2-nul...

Levels Defined by CD 44 and CD 122 Expression Subsets of Memory Phenotype CD 8 T Cells Differential In Vivo Persistence of Two Jacqueline